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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 2 — Mar. 4, 2013

In vivo measurement of the average refractive index of the human crystalline lens using optical coherence tomography

Carolina de Freitas, Marco Ruggeri, Fabrice Manns, Arthur Ho, and Jean-Marie Parel  »View Author Affiliations


Optics Letters, Vol. 38, Issue 2, pp. 85-87 (2013)
http://dx.doi.org/10.1364/OL.38.000085


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Abstract

We present a method for measuring the average group refractive index of the human crystalline lens in vivo using an optical coherence tomography (OCT) system which, allows full-length biometry of the eye. A series of OCT images of the eye including the anterior segment and retina were recorded during accommodation. Optical lengths of the anterior chamber, lens, and vitreous were measured dynamically along the central axis on the OCT images. The group refractive index of the crystalline lens along the central axis was determined using linear regression analysis of the intraocular optical length measurements. Measurements were acquired on three subjects of age 21, 24, and 35 years. The average group refractive index for the three subjects was, respectively, n=1.41, 1.43, and 1.39 at 835 nm.

© 2013 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(330.5370) Vision, color, and visual optics : Physiological optics

ToC Category:
Imaging Systems

History
Original Manuscript: September 3, 2012
Revised Manuscript: November 21, 2012
Manuscript Accepted: December 5, 2012
Published: January 4, 2013

Virtual Issues
Vol. 8, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Carolina de Freitas, Marco Ruggeri, Fabrice Manns, Arthur Ho, and Jean-Marie Parel, "In vivo measurement of the average refractive index of the human crystalline lens using optical coherence tomography," Opt. Lett. 38, 85-87 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-2-85

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