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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 3 — Apr. 4, 2013

Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source

WooJhon Choi, Benjamin Potsaid, Vijaysekhar Jayaraman, Bernhard Baumann, Ireneusz Grulkowski, Jonathan J. Liu, Chen D. Lu, Alex E. Cable, David Huang, Jay S. Duker, and James G. Fujimoto  »View Author Affiliations


Optics Letters, Vol. 38, Issue 3, pp. 338-340 (2013)
http://dx.doi.org/10.1364/OL.38.000338


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Abstract

Despite the challenges in achieving high phase stability, Doppler swept-source/Fourier-domain optical coherence tomography (OCT) has advantages of less fringe washout and faster imaging speeds compared to spectral/Fourier-domain detection. This Letter demonstrates swept-source OCT with a vertical cavity surface-emitting laser light source at 400 kHz sweep rate for phase-sensitive Doppler imaging, measuring pulsatile total retinal blood flow with high sensitivity and phase stability. A robust, simple, and computationally efficient phase stabilization approach for phase-sensitive swept-source imaging is also presented.

© 2013 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(280.2490) Remote sensing and sensors : Flow diagnostics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 20, 2012
Revised Manuscript: December 11, 2012
Manuscript Accepted: December 28, 2012
Published: January 28, 2013

Virtual Issues
Vol. 8, Iss. 3 Virtual Journal for Biomedical Optics

Citation
WooJhon Choi, Benjamin Potsaid, Vijaysekhar Jayaraman, Bernhard Baumann, Ireneusz Grulkowski, Jonathan J. Liu, Chen D. Lu, Alex E. Cable, David Huang, Jay S. Duker, and James G. Fujimoto, "Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source," Opt. Lett. 38, 338-340 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-3-338

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