We propose an inter-Ascan speckle decorrelation based method that can quantitatively assess blood flow normal to the direction of the optical coherence tomography imaging beam. To validate this method, we performed a systematic study using both phantom and in vivo animal models. Results show that our speckle analysis method can accurately extract transverse flow speed with high spatial and temporal resolution.
© 2013 Optical Society of America
Original Manuscript: December 13, 2012
Manuscript Accepted: January 18, 2013
Published: March 1, 2013
Vol. 8, Iss. 4 Virtual Journal for Biomedical Optics
Xuan Liu, Yong Huang, Jessica C. Ramella-Roman, Scott A. Mathews, and Jin U. Kang, "Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis," Opt. Lett. 38, 805-807 (2013)