OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 4 — May. 22, 2013

Decoupling of geometric thickness and refractive index in quantitative phase microscopy

Nelson Cardenas and Samarendra Mohanty  »View Author Affiliations

Optics Letters, Vol. 38, Issue 6, pp. 1007-1009 (2013)

View Full Text Article

Enhanced HTML    Acrobat PDF (376 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



In quantitative phase imaging, a priori knowledge of either refractive index or physical thickness is used to estimate the change in one of these parameters. Here, we report a method for decoupling geometric thickness from refractive index in quantitative phase microscopy.

© 2013 Optical Society of America

OCIS Codes
(070.6110) Fourier optics and signal processing : Spatial filtering
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(170.0180) Medical optics and biotechnology : Microscopy

ToC Category:
Instrumentation, Measurement, and Metrology

Original Manuscript: August 22, 2012
Revised Manuscript: February 16, 2013
Manuscript Accepted: February 19, 2013
Published: March 15, 2013

Virtual Issues
Vol. 8, Iss. 4 Virtual Journal for Biomedical Optics

Nelson Cardenas and Samarendra Mohanty, "Decoupling of geometric thickness and refractive index in quantitative phase microscopy," Opt. Lett. 38, 1007-1009 (2013)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. W. Yang, S. Lee, J. Lee, Y. Bae, and D. Kim, J. Biomed. Opt. 15, 045005 (2010). [CrossRef]
  2. Y. K. Park, M. Diez-Silva, G. Popescu, G. Lykotrafitis, W. S. Choi, M. S. Feld, and S. Suresh, Proc. Natl. Acad. Sci. USA 105, 13730 (2008). [CrossRef]
  3. N. Cardenas, L. Yu, and S. K. Mohanty, Proc. SPIE 7897, 78971J (2011). [CrossRef]
  4. J. W. Kang, N. Lue, C. R. Kong, I. Barman, N. C. Dingari, S. J. Goldfless, J. C. Niles, R. R. Dasari, and M. S. Feld, Biomed. Opt. Express 2, 2484 (2011). [CrossRef]
  5. C. Y. Xu, C. Vinegoni, T. S. Ralston, W. Luo, W. Tan, and S. A. Boppart, Opt. Lett. 31, 1079 (2006). [CrossRef]
  6. F. Zernike, Science 121, 345 (1955). [CrossRef]
  7. S. Gonzalez and Z. Tannous, J. Am. Acad. Dermatol. 47, 869 (2002). [CrossRef]
  8. S. F. Nee and H. E. Bennett, J. Opt. Soc. Am. A 10, 2076 (1993). [CrossRef]
  9. C. B. Kim and C. B. Su, Meas. Sci. Technol. 15, 1683(2004). [CrossRef]
  10. A. Y. Nassif, Appl. Opt. 36, 779 (1997). [CrossRef]
  11. F. L. McCrackin, E. Passaglia, R. R. Stromberg, and H. L. Steinberg, J. Res. Natl. Inst. Stan. 106, 589 (2001). [CrossRef]
  12. P. Marteau, G. Montixi, J. Obriot, T. K. Bose, and J. M. S. Arnaud, Rev. Sci. Instrum. 62, 42 (1991). [CrossRef]
  13. E. Cuche, P. Marquet, and C. Depeursinge, Appl. Opt. 38, 6994 (1999). [CrossRef]
  14. T. Ikeda, G. Popescu, R. R. Dasari, and M. S. Feld, Opt. Lett. 30, 1165 (2005). [CrossRef]
  15. E. Sanchez-Ortiga, P. Ferraro, M. Martinez-Corral, G. Saavedra, and A. Doblas, J. Opt. Soc. Am. A 28, 1410(2011). [CrossRef]
  16. N. Cardenas, S. Kumar, and S. Mohanty, Appl. Phys. Lett. 101, 203702 (2012). [CrossRef]
  17. B. Bhaduri, H. Pham, M. Mir, and G. Popescu, Opt. Lett. 37, 1094 (2012). [CrossRef]
  18. N. Cardenas, N. Ingle, L. Yu, and S. K. Mohanty, Proc. SPIE 7904, 790409 (2011).
  19. R. M. Goldstein, H. A. Zebker, and C. L. Werner, Radio Sci. 23, 713 (1988). [CrossRef]
  20. P. Ferraro, S. De Nicola, A. Finizio, G. Coppola, S. Grilli, C. Magro, and G. Pierattini, Appl. Opt. 42, 1938 (2003). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1. Fig. 2. Fig. 3.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited