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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 4 — May. 22, 2013

High-sensitivity ultrasound-modulated optical tomography with a photorefractive polymer

Yuta Suzuki, Puxiang Lai, Xiao Xu, and Lihong Wang  »View Author Affiliations


Optics Letters, Vol. 38, Issue 6, pp. 899-901 (2013)
http://dx.doi.org/10.1364/OL.38.000899


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Abstract

By detecting ultrasonically tagged diffuse light, ultrasound-modulated optical tomography images optical contrast with ultrasonic resolution deep in turbid media, such as biological tissue. However, small detection etendues and weak tagged light submerged in strong untagged background light limit the signal detection sensitivity. In this Letter, we report the use of a large-area (5cm×5cm) photorefractive polymer film that yields more than 10 times detection etendue over previous detection schemes. Our polymer-based system enabled us to resolve absorbing objects embedded inside diffused media thicker than 80 transport mean free paths, by using moderate light power and short ultrasound pulses.

© 2013 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6960) Medical optics and biotechnology : Tomography
(190.7070) Nonlinear optics : Two-wave mixing
(080.2175) Geometric optics : Etendue

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 26, 2012
Revised Manuscript: January 30, 2013
Manuscript Accepted: February 10, 2013
Published: March 12, 2013

Virtual Issues
Vol. 8, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Yuta Suzuki, Puxiang Lai, Xiao Xu, and Lihong Wang, "High-sensitivity ultrasound-modulated optical tomography with a photorefractive polymer," Opt. Lett. 38, 899-901 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-6-899

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