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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 9, Iss. 3 — Mar. 6, 2014

Convolution model of the diffuse reflectance for layered tissues

S. B. Rohde and A. D. Kim  »View Author Affiliations


Optics Letters, Vol. 39, Issue 1, pp. 154-157 (2014)
http://dx.doi.org/10.1364/OL.39.000154


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Abstract

We present an explicit model for the diffuse reflectance due to a collimated beam of light incident normally on layered tissues. This model is derived using the corrected diffusion approximation applied to a layered medium, and it takes the form of a convolution with an explicit kernel and the incident beam profile. This model corrects the standard diffusion approximation over all source–detector separation distances provided the beam is sufficiently wide compared to the scattering mean free path. We validate this model through comparison with Monte Carlo simulations. Then we use this model to estimate the optical properties of an epithelial layer from Monte Carlo simulation data. Using measurements at small source–detector separations and this model, we are able to estimate the absorption coefficient, scattering coefficient, and anisotropy factor of epithelial tissues efficiently with reasonable accuracy.

© 2013 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(290.7050) Scattering : Turbid media
(010.5620) Atmospheric and oceanic optics : Radiative transfer

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 15, 2013
Revised Manuscript: October 31, 2013
Manuscript Accepted: November 21, 2013
Published: December 24, 2013

Virtual Issues
Vol. 9, Iss. 3 Virtual Journal for Biomedical Optics

Citation
S. B. Rohde and A. D. Kim, "Convolution model of the diffuse reflectance for layered tissues," Opt. Lett. 39, 154-157 (2014)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-39-1-154

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