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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 24 — Dec. 15, 2013
  • pp: 5228–5231

Absolute photoacoustic thermometry in deep tissue

Junjie Yao, Haixin Ke, Stephen Tai, Yong Zhou, and Lihong V. Wang  »View Author Affiliations

Optics Letters, Vol. 38, Issue 24, pp. 5228-5231 (2013)

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Photoacoustic thermography is a promising tool for temperature measurement in deep tissue. Here we propose an absolute temperature measurement method based on the dual temperature dependences of the Grüneisen parameter and the speed of sound in tissue. By taking ratiometric measurements at two adjacent temperatures, we can eliminate the factors that are temperature irrelevant but difficult to correct for in deep tissue. To validate our method, absolute temperatures of blood-filled tubes embedded 9mm deep in chicken tissue were measured in a biologically relevant range from 28°C to 46°C. The temperature measurement accuracy was 0.6°C. The results suggest that our method can be potentially used for absolute temperature monitoring in deep tissue during thermotherapy.

© 2013 Optical Society of America

OCIS Codes
(120.6780) Instrumentation, measurement, and metrology : Temperature
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Remote Sensing and Sensors

Original Manuscript: August 27, 2013
Manuscript Accepted: October 19, 2013
Published: December 3, 2013

Virtual Issues
Vol. 9, Iss. 2 Virtual Journal for Biomedical Optics

Junjie Yao, Haixin Ke, Stephen Tai, Yong Zhou, and Lihong V. Wang, "Absolute photoacoustic thermometry in deep tissue," Opt. Lett. 38, 5228-5231 (2013)

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