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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 2 — Feb. 17, 2011

Bimetallic chips for a surface plasmon resonance instrument

Y. Chen, R. S. Zheng, D. G. Zhang, Y. H. Lu, P. Wang, H. Ming, Z. F. Luo, and Q. Kan  »View Author Affiliations

Applied Optics, Vol. 50, Issue 3, pp. 387-391 (2011)

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In this work we have replaced a commonly used Au film with an Au/Ag bimetallic film working as the sensing chip in the commercial surface plasmon resonance (SPR) instrument, Biacore 3000. The bimetallic chip gives out sharper SPR dip than that by the chip made of an Au film. The applicability and stability of the bimetallic chip on the Biacore 3000 are tested by real-time monitoring of biological coupling processes between sulfamethoxazole (SMX) and anti-SMX, which is useful in rapid detection of contaminations in food products. The bimetallic chip performs stably in 6 times’ usage and regeneration. Our experiment is helpful to push the bimetallic film into real applications in commercial SPR instruments.

© 2011 Optical Society of America

OCIS Codes
(230.4170) Optical devices : Multilayers
(240.6680) Optics at surfaces : Surface plasmons
(280.1415) Remote sensing and sensors : Biological sensing and sensors

ToC Category:
Optics at Surfaces

Original Manuscript: October 6, 2010
Revised Manuscript: December 1, 2010
Manuscript Accepted: December 3, 2010
Published: January 20, 2011

Virtual Issues
Vol. 6, Iss. 2 Virtual Journal for Biomedical Optics

Y. Chen, R. S. Zheng, D. G. Zhang, Y. H. Lu, P. Wang, H. Ming, Z. F. Luo, and Q. Kan, "Bimetallic chips for a surface plasmon resonance instrument," Appl. Opt. 50, 387-391 (2011)

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