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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 12 — Dec. 19, 2012

Numerical simulation of the influence of the elastic modulus of a tumor on laser-induced ultrasonics in soft tissue

Rong Rong An, Xiao Sen Luo, and Zhong Hua Shen  »View Author Affiliations

Applied Optics, Vol. 51, Issue 32, pp. 7869-7876 (2012)

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The influence of the elastic modulus of a tumor (EMT) on the laser-generated thermoelastic force source and ultrasound waves are investigated by using the finite element method. Taking into account the effects of thermal diffusion, optical penetration, and finite duration of laser pulse, the transient temperature distribution is obtained. Applying this temperature field to structure analyses as thermal loading, the thermoelastic stress field and laser-induced ultrasound wave in soft tissues are obtained. The results show that there is a linear correlation between the maximum compressive stress and the elastic modulus of tissues. It is also shown that the features and frequency regions of the laser-induced ultrasound waveform have a close relationship with the EMT, which has been further verified by a corresponding experiment.

© 2012 Optical Society of America

OCIS Codes
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(280.3375) Remote sensing and sensors : Laser induced ultrasonics
(070.7345) Fourier optics and signal processing : Wave propagation

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 14, 2012
Revised Manuscript: September 19, 2012
Manuscript Accepted: October 16, 2012
Published: November 9, 2012

Virtual Issues
Vol. 7, Iss. 12 Virtual Journal for Biomedical Optics

Rong Rong An, Xiao Sen Luo, and Zhong Hua Shen, "Numerical simulation of the influence of the elastic modulus of a tumor on laser-induced ultrasonics in soft tissue," Appl. Opt. 51, 7869-7876 (2012)

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